My latest trip was to Spertus and it was a little underwhelming. It's a cool building and I like that they give you a pamphlet so that you can take a self-guided tour, but there's really not a whole lot to see. It's kind of like if Loyola or DePaul started giving tours of all of the Catholic stuff they have on their campus. Yeah, it's there, but it's not really enough to justify taking a tour.
I'm being a little harsh. They did have a somewhat interesting exhibit on Jewish history in Chicago.